Emerging infectious diseases, such as the H1N1 influenza virus, require a multi-faceted approach in order to identify, evaluate, and control their spread. The H1N1 virus is a prime example of the importance of controlling the spread of an infectious disease in the workplace in order to ensure continuity of operations in any organization, including government agencies, military organizations, health-care facilities and small businesses. Using the H1N1 virus as an example, this roundtable will highlight proven occupational safety and health practices that can be implemented in the workplace to minimize disease transmission. Experts participating in the roundtable will discuss the background of H1N1, emerging infectious disease epidemiology (including differences from traditional epidemiology), proper engineering and personal protective equipment control selection, surveillance methods after an outbreak, and application of lessons learned after the outbreak. While using H1N1 as an example, the tools provided can be applied to other infectious disease outbreaks.